CHRONICITY AND DETERIORATION IN MANIC DEPRESSIVE CASES

Juvenile Manic Depressive Psychosis — Report of 3 Cases

Three patients, one female and two males, with bipolar affective psychosis beginning at the ages of twelve, nine and fourteen years, are described. The symptomatology in all the three patients was similar to that of the adult manic depressive psychosis and the response to lithium was good.

The Depressive Phase of Manic-Depressive Insanity

IT iS to the genius of Kraepelin, whose death in 1926 must have spared him the pain of encountering Nazism, that we owe both the title and our present conception of manic-depressive insanity. This conception embraces far more than the clinical close relationship which sometimes exists between states of mania and states of melancholia. A good deal, in fact, was known about this relationship befo...

[Affective equivalents in depressive and manic-depressive patients].

Genetics of manic depressive illness.

Manic depressive illness is a common and frequently debilitating familial psychiatric disorder. Efforts to understand the mechanisms of inheritance have been hindered by the complexity of the phenotype, which may range from benign mood swings to chronic psychosis, and by apparently nonmendelian modes of transmission. Early reports of linkage to chromosomal loci have fallen into doubt; however t...

[Attempted suicide during depressive (unipolar) and manic depressive (bipolar) psychoses].